Saito graduated in Western painting from Tokyo School of Fine Arts. He went to Paris in 1906 and returned to Japan having studied Neo-Impressionism and other trends. He conveyed this new tendency to the Bunten and Nikakai of the time. He traveled to France again in 1920 and settled there. Though he did not leave so many works throughout his lifetime, he is known for his vivid pointillist works, which reach a high degree of perfection.