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His technical versatility is apparent in his diverse works on paper and canvas, primarily in oil, watercolor, and pen. Guiragossian's pieces move between abstraction and figuration to capture the essence of the human form. Guiragossian uses long, vertical brushstrokes to depict the bodies of his figures as abstracted and elongated so that the imagery has echoes of Byzantine icons. A true Modernist, Guiragossian began producing during the late sixties complete abstract paintings. Applying bright, bold color in blocks to the canvas, Guiragossian then left parts of the surface untouched, generating depth and movement through a creative embrace of negative space.