The Virgin and Saint John the Evangelist mourn, and Saint Mary Magdalene clutches the foot of the cross, the other two Maries stand behind her.
Joseph of Arimathaea and Nicodemus appear in the background on the left with a ladder to take down the body of Christ, while on the right soldiers return to Jerusalem.
Massys was the leading artist in Antwerp in the early 1500s. This was probably painted in about 1515.
This picture was presented by Queen Victoria at the Prince Consort's wish, 1863.