Maccarese is a locality in Lazio, Italy, in the Metropolitan City of Rome. It is administratively divided between the Municipalities of Rome and Fiumicino, of which it is a frazione.
It was entirely part of the Municipality of Rome until 1993, when the former Circoscrizione XIV, which included a part of the hamlet, became the autonomous Municipality of Fiumicino.
Crossed by the Arrone river, which flows into the Tyrrhenian Sea, the locality - which extends from the Fiumicino Airport to the sea and borders Fregene to the north-west - is best known for the homonymous farm Maccarese S.p.A., established in 1925 following the reclamation works of this area of the Ager Romanus.