Lafayette is a city in the U.S. state of Louisiana. The city is the most populous and parish seat of Lafayette Parish, and is located along the Vermilion River. It is Louisiana's fourth largest incorporated municipality by population and the 219th most populous in the United States, with a 2019 census–estimated population of 126,199; the consolidated city–parish's population was 244,390 in 2019. The Greater Lafayette metropolitan area was Louisiana's third largest metropolitan statistical area with a population of 489,207 at the 2019 American Community Survey, overtaking the Shreveport–Bossier City metropolitan area.
Nicknamed "The Hub City", the city and parish of Lafayette are also known as the "Heart of Acadiana", and have a consolidated city-parish government. The city, metropolitan area and Acadiana region are major centers for the technology industry, and home to the University of Louisiana at Lafayette. Lafayette is also a major center for health care and social services, aerospace, banking and retail.