Syncletica of Alexandria was a Christian saint and Desert Mother from Roman Egypt in the 4th century. She is the subject of the Vita S. Syncleticæ, a Greek hagiography purportedly by Athanasius of Alexandria but not written in fact before 450. She then appears as amma Syncletica, an anchorite to whom are attributed twenty-eight sayings in the Apophthegmata Patrum, compiled c.480–500.