Djedkhonsuefankh was a High Priest of Amun in Thebes believed to have been in office from 1046–1045 BC.
It is often assumed that he was a son of Pinedjem I who succeeded his brother Masaherta during a time of great turmoil in the city of Thebes. Von Beckerath has even suggested that it is possible that he died a violent death, accounting for his very short reign. Kitchen considered this possibility as well, but also stated that "this may be an over-dramatic interpretation of his brief rule".
All we actually know of his existence is the bare mention of his name on the coffin of his son. There it reads, according to Cecil Torr:
"[...]re, son of the first prophet of Amun, Djed-Khons-ef-ankh, son of the Lord of the Two Lands, Pinedjem, Beloved of Amun, first prophet of Amun", with the name Pinedjem enclosed in a cartouche.
Djedkhonsuefankh is supposed to have been succeeded as High Priest by his brother Menkheperre, which seems to imply that his son "[...]re" either predeceased him, was too young to succeed or was simply passed over for other reasons.