Florida is a currently uninhabited village in Monroe County, Missouri, United States. It is located at the intersection of Missouri Route 107 and State Route U on the shores of Mark Twain Lake. The population was 200, per the census data in the 1911 Cram's World Atlas. The population was however down to nine residents according to the 2000 United States Census, and following the 2010 Census, the village was reported as uninhabited. The Mark Twain Birthplace State Historic Site is located in Florida, with Mark Twain State Park nearby.