Beginning at the tender age of seven, Meheruddin started to learn the Sarangi from his father, Kamu Khan. He later also became an expert in playing multiple traditional instruments such as the Alghoza, Morchang and Surinda. He has a stunning range of collaborations to his credit including ones with Zakir Hussain, Allan Water, Zingaro, Ravi Shankar, Hariprasad Chaurasia, and others. He is a Guru to the children of his village.