This is one of the panels of the high altarpiece of the church of S. Alessandro, Brescia. It shows Saint Jerome, a monk and scholar who lived in Constantinople and Rome around AD341-420. He was appointed as secretary to Pope Damasus I for whom he made the first translation of the Bible in Latin. He was also a hermit who spent many years in the desert, and here, he is depicted in penitence with his emblems of a lion, a stone and a crucifix.