The Cathedral of St. James is an expression of the deepest human spirituality, inclined toward the transcendental. Due to the extratemporal artistic values and cultural significance, the cathedral is still today a source of inspiration for many writers, poets, artists and scientists. The Cathedral of St James is the fruitful outcome of considerable interchanges of influences between the three culturally different regions of Northern Italy, Dalmatia, and Tuscany in the 15th and 16th centuries. These interchanges created the conditions for unique and outstanding solutions to the technical and structural problems of constructing the cathedral vaulting and dome.