Free Imperial Knight Andries de Graeff was a very powerful member of the Amsterdam branch of the De Graeff - family during the Dutch Golden Age. He became a mayor of Amsterdam and a powerful Amsterdam regent after the death of his older brother Cornelis de Graeff. Like him and their father Jacob Dircksz de Graeff he opposed the house of Orange. In the mid-17th century he controlled the finances and politics.
Andries de Graeff followed in his father's and brother's footsteps and, between 1657 and 1672, was appointed mayor some seven times. De Graeff was a member of a family of regents who belonged to the republican political movement also referred to as the ‘state oriented’, as opposed to the Royalists. Andries was called the last regent and mayor from the dynasty of the "Graven", who was powerful and able enough to ruled the city of Amsterdam.
De Graeff was a Free Imperial Knight of the Holy Roman Empire, an Ambachtsheer from Urk en Emmeloord, during the late 1650s chiefcouncillor of the Admiralty of Amsterdam, chieflandholder of the Watergraafsmeer and dijkgraaf van Nieuwer-Amstel.
Together with his brother Cornelis De Graeff he became an illustrious Patron and Art collector.