Messina Cathedral is a Roman Catholic cathedral located in Messina, Sicily. Formerly the episcopal seat of the Diocese of Messina, it became in 1986 the archiepiscopal seat of the Archdiocese of Messina-Lipari-Santa Lucia del Mela.
In June 1947 Pope Pius XII granted it the status of a minor basilica.
The current building is the final result of some twentieth-century reconstructions, which took place following the disastrous earthquake that struck Messina in 1908 and the considerable damage that resulted from the heavy aerial bombardment in World War II.
The tower houses the Messina astronomical clock, the largest astronomical clock in the world.