Southern Plains Indian Museum is a Native American museum located in Anadarko, Oklahoma. It was opened in 1948 under a cooperative governing effort by the United States Department of the Interior and the Oklahoma state government. The museum features cultural and artistic works from Oklahoma tribal peoples of the Southern Plains region, including the Caddo, Chiricahua Apache, Comanche, Delaware Nation, Kiowa, Plains Apache, Southern Arapaho, Southern Cheyenne, and Wichita.