Larissa is the capital and largest city of the Thessaly region in Greece. It is the fifth-most populous city in Greece with a population of 144,651 according to the 2011 census. It is also capital of the Larissa regional unit. It is a principal agricultural centre and a national transport hub, linked by road and rail with the port of Volos, the cities of Thessaloniki and Athens. The municipality of Larissa has 162,591 inhabitants, while the regional unit of Larissa reached a population of 284,325.
Legend has it that Achilles was born here. Hippocrates, the "Father of Medicine", died here. Today, Larissa is an important commercial, transportation, educational, agricultural and industrial centre of Greece.