Tlaxiaco is a city, and its surrounding municipality of the same name, in the Mexican state of Oaxaca. It is located in the Tlaxiaco District in the south of the Mixteca Region, with a population of about 17,450.
The city is formally known as Heroica Ciudad de Tlaxiaco in honour of a battle waged there during the 1862–67 French invasion. Tlaxiaco is a Nahuatl name containing the elements tlachtli, quiahuitl, and -co. It thus approximates to "Place where it rains on the ball court". Its name in the Mixtec language is Ndijiinu, which means "good view".
On January 1, 2019, Tlaxiaco found itself in the international news, when newly elected mayor, Alejandro Aparicio, was assassinated in the street shortly after taking his oath of office.