Mission La Purísima Concepción, or La Purísima Mission is a Spanish mission in Lompoc, California. It was established on December 8, 1787 by the Franciscan order. The original mission complex south of Lompoc was destroyed by an earthquake in 1812, and the mission was rebuilt at its present site a few miles to the northeast.
The mission is part of the larger La Purísima Mission State Historic Park, part of the California State Parks system, and along with Mission San Francisco de Solano is one of only two of the Spanish missions in California that is no longer governed by the Catholic Church. It is currently the only example in California of a complete Spanish Catholic mission complex, and was designated a National Historic Landmark in 1970.