Zuilichem is a village in the Dutch province of Gelderland. It is a part of the municipality of Zaltbommel, and lies about 11 km east of Gorinchem.
Zuilichem was a separate municipality until 1955, when it was merged with Brakel.
In 2001, the village of Zuilichem had 764 inhabitants. The built-up area of the village was 0.19 km², and contained 298 residences.
The statistical area "Zuilichem", which also can include the peripheral parts of the village, as well as the surrounding countryside, has a population of around 1490.
The seventeenth-century Dutch scientist and polymath Constantijn Huygens purchased the manor and title of Zuilichem in 1630.