St. Charles Borromeo Church is a church in central Antwerp, located on the Hendrik Conscience square. It was built in 1626 as the Jesuit church of Antwerp, which was closed in 1773. It was rededicated in 1779 to Saint Charles Borromeo. The church was formerly known for 39 ceiling pieces by Rubens that were lost in a fire when lightning struck the church on 18 July 1718.