Priene was an ancient Greek city of Ionia located at the base of an escarpment of Mycale, about 6 kilometres north of what was then the course of the Maeander River. It was 67 kilometres from ancient Anthea, 15 kilometres from ancient Aneon and 25 kilometres from ancient Miletus. The city was built on the sea coast, overlooking the former Latmian Gulf of the Aegean. It was developed on steep slopes and terraces extending from sea level to a height of 380 metres above sea level at the top of the escarpment. Because of siltation from the river filling the bay over several centuries, the city is now an inland site. It is located at a short distance west of the modern village Güllübahçe Turun in the Söke district of Aydın Province, Turkey.
Priene is known to have been the site of high-quality Hellenistic art and architecture. The city's original position on Mount Mycale has never been discovered; however, it is believed that it was on a peninsula with two harbours. Priene never held a great deal of political importance due to the city's relatively limited size, as it is believed around four to five thousand inhabitants occupied the region.