San Isidro, officially the Municipality of San Isidro, is a 3rd class municipality in the province of Davao Oriental, Philippines. According to the 2020 census, it has a population of 33,664 people.
San Isidro is one of the "gulf towns" of Davao Oriental whose shorelines stretch along Davao Gulf. Other gulf towns are Banaybanay, Lupon and Governor Generoso.