Sandersleben is a town and a former municipality in the Mansfeld-Südharz district, in Saxony-Anhalt, Germany. It is situated on the river Wipper, approx. 17 km north of Eisleben. Since 1 January 2010, it has been administered as part of Arnstein.
Sandersleben station lies on the Halle–Vienenburg and the Berlin-Blankenheim railways.
Notable residents of Sandersleben include:
Bernhard von Krosigk
Gotthold Salomon
Georg Heinrich von Berenhorst