Waynesboro, is an independent city in the Commonwealth of Virginia. As of the 2010 census, the population was 21,006.
The city is surrounded by Augusta County and is named for General Anthony Wayne. Waynesboro is located in the Shenandoah Valley, near many important historical markers of the Civil War and Shenandoah National Park. A portion of Interstate 64 falls within the city limits of Waynesboro, and the Blue Ridge Parkway, Skyline Drive, and the Appalachian Trail are less than 5 miles away. Norfolk Southern Railway trackage runs through the east side of the city. The South River, a tributary of the Shenandoah River, flows through the city.
A large former DuPont plant and the associated Benger Laboratory where spandex was invented, as well as a large textile mill called Wayn-Tex, were significant employers for residents through much of the 20th century. The DuPont plant was later sold to Koch Industries as part of the subsidiary company Invista. In January of 2019, the plant was again sold to Chinese luxury apparel firm Shandong Ruyi Group and rebranded as The Lycra Company.