The Italian Renaissance was a large movement from the art of the Middle Ages. It made use of perspective and a more realistic representation of the human body, and was just overall closer to representing what one would see with their own eye.
With the exception of the Mona Lisa, also by da Vinci, The Last Supper is one of the most famous paintings of the Renaissance. It shows perspective as the background closes to a vanishing point
This painting, by Giorgione, also shows perspective and a more realistic human. The background trends off to the left, and you can see less detail off in the distance. The people have normal skin also
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