Brainbow is a process by which individual neurons in the brain can be distinguished from neighboring neurons using fluorescent proteins. By randomly expressing different ratios of red, green, and blue derivatives of green fluorescent protein in individual neurons, it is possible to flag each neuron with a distinctive color. To trace the longer pathways that interconnect different brain regions, CBS labs developed a genetic method to label each individual nerve cell a different color to identify and track axons and dendrites over long distances. With light microscopy, scientists image the branching patterns and connections of all the axons within a region of the nervous system in transgenic mice that express a number of different fluorescent proteins in individual neurons. The idea here is to color-code the individual “wires” and “nodes.”
The technique was originally developed in the spring of 2007 by a team led by Jeff W. Lichtman and Joshua R. Sanes, both professors of Molecular & Cellular Biology at Harvard University.
The Barbican's AI: More than Human (16 May-26 Aug 2019) is an major exhibition exploring creative and scientific developments in artificial intelligence demonstrating its potential to revolutionise our lives. Part of Life Rewired, the Barbican's 2019 season exploring what it means to be human when technology is changing everything.