Amache was named after a Cheyenne woman who married John Prowers, a rancher for whom the county is named.
Unlike other centers built on federal land, the 10,500 acres of the Granada Relocation Center were acquired by purchase or condemnation of eighteen privately owned ranches and farms, arousing the anger of some local residents.
Amache had the smallest population of the relocation centers but was the tenth largest "city" in Colorado.
Instead of post and pier foundations, barracks had slab foundations, or concrete perimeter foundations with brick floors. The buildings also had asbestos shingle siding, rather than the tarpaper common at most of the other relocation centers.
The high school, with an auditorium/gymnasium building, was complete in 1943. This was the most expensive building constructed in Prowers County up to that time. Some local residents and politicians were opposed to the construction of a new elementary school. Instead, elementary classes were held in the barracks of Block 8H.
In spite of its small population, Granada had one of the largest and most diversified agricultural enterprises of the ten relocation centers. Granada had the advantage over the other centers in that its fields and canals were already in place and needed only minor repairs.
A small building at the cemetery may have been used by the internees to store cremated remains.
After the camp closed, its central area was sold to the town of Granada for $2,500.00.