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This bust is identified as Cleopatra, ancient queen of Egypt, by her crown and by the small serpent that decorates the base. Once Cleopatra lost all hope of regaining control of Egypt from the Romans, she is believed to have committed suicide by the poisonous bite of a snake. The bust reflects an ancient Roman prototype and was made by an artist whose nickname, Antico, resulted from his exceptional skill in such ancient techniques as bronze casting. The bust probably belonged to Isabella d'Este, Marchioness of Mantua.

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