The nave's vaulted ceiling spans 30 metres. It is the "most accomplished realisation of the late Mediaeval ambition of covering the greatest possible span with the lowest number of supports" (Kubler). In this open space, which abounds in regal symbolism, the profusion of ornamentation reaches its zenith.
In the left arm of the transept rest the remains of the Cardinal-King Dom Henrique and the children of Manuel I. In the right arm is the tomb of King Sebastião and the descendants of King João III.