Published in the reign of D. Maria II, it was the first official Portuguese pharmacopoeia with compulsory character in all pharmacies. The publishing of an official pharmacopoeia in Portugal was, according to the Pombaline Statutes of the University of Coimbra (1772), the responsibility of the Faculty of Medicine. It was published twenty-two years after the publication of the statutes and its author was Francisco Tavares. He was a professor at the Faculty of Medicine of the University of Coimbra and son of a famous Coimbra apothecary. He taught, among other subjects, Medical Substances and Pharmaceutical Art.