As recorded by 16th century sources from the Vallombrosan church of Santa Trinita in Florence, the panel (1280-90) was originally on the main altar. In the 17th century it was in the infirmary of the convent and from 1765 it was moved to the sacristy and then transported to the Accademia in 1810, following the suppression of religious orders by the French. It has been in the Uffizi since 1919. The writing on the scrolls refer to the mystery of the Incarnation and to the virginity of Mary.