Mayfreen Ryntathiang founded and heads Grassroot, an NGO with its main objective being to encourage, empower and enhance people’s responsibility for societal change. Mayfereen is actively associated with World Mountain People Association (WMPA). International Centre for Integrated Mountain Development (ICIMOD) to name a few. During her years of contribution to the society, she has also visited various international conferences speaking her mind of human rights issues. She was a part of the Mountain Community Team to present a motion on Anti uranium mining in Meghalaya at the UNESCO, Paris, represented the Presbyterian Church of India in Bangkok, Thailand in a workshop on Human Rights and was part of a South East Asian exposure trip on Violence against Women in Bangladesh. In 2016, she represented India at the United Nations Permanent Forum of Indigenous issues, at the UN Headquarters, New York, USA to lend a voice on land and cultural rights.