Most medical works of the "Biblioteca Bipontina" originate from the collection of the Zweibrücken based town doctor Johann Theophil Hoeffel (1704-1781), whose library was bought by Karl August.
Most of the publications are written in German and represent different medical directions, amongst them anatomy and obstetrics.
The "Dreck-Apotheke" of the town doctor Paullini (1643-1712) from Eisenach is based on the ancient theories of body fluids and traditional medical practices. His recommendations concerning the therapeutical use of excretions were already controversial amongst his contemporaries.