Neptune and Amphitrite are standing on a low plinth surrounded by water in a domed structure supported by columns. We are looking into the mighty sea-god's shrine, in which he appears to us with his spouse in statuesque symmetry, but with a sense of being a living physical presence. On the plinth is the artist's proud signature "IOANNES MALBODIVS PINGEBAT", dated 1516. Top right are the device and name of the patron, Philip of Burgundy (1464-1524). This large picture was part of a lavish decoration that Philip had commissioned for his castle. Gossaert had accompanied his patron to Rome in 1508, where he drew ancient buildings and sculptures for him. This was one of the earliest Italian journeys undertaken by Netherlandish artists, which led them to address and come to terms with Italian art. This impressive composition is inspired by these travels and impressions, and also by ideas derived from Albrecht Dürer and Jacopo de' Barbari.