Murillo's production was one of the vastest ones in the Spanish Golden Age: his studio was entrusted with the production of dozens of versions of the subject, along with the devotion that extended to all of the Spanish kingdoms. Some versions found their way to New Spain, where the gentleness represented by the Sevillian broke with the most traditional pictorial schemes. Their illumination, iconographic models, application of color and diaphanous effect maintained a close dialog with local painters such as Cristóbal de Villalpando, Juan Rodríguez Juárez, José de Ibarra and Miguel Cabrera.
This latter painter copied some aspects of Murillo's painting, but incorporated others from the model described by Pacheco, such as the crown with twelve stars, allusions to the Litany of Loreto, the moon and the defeat of the serpent.