In 1922, the Russian geophysicist Alexander Friedmann, who lectured at the University of Kyiv in 1916-1917, designed a mathematical model of the Universe that expands. Scientists applied the model in retrospective to understand the Universe emerged as a result of explosion. In 1948, George Gamow, a famous American mathematician of the Ukrainian descent (born in 1904 in Odesa) proposed a physical model of the Universe origins known as the Big Bang. Gamow predicted the existence of cosmic microwave background radiation, which was scientifically described only in 1964 that proved Gamow’s theory.