This is one of four early masterpieces by Giovanni di Paolo in the Walters. It was originally part of a predella (paintings on the base of an altarpiece) in the chapel of the Malavolti family in the church of San Domenico in Siena. The main altar panel, dated 1426 and depicting the Virgin and Child flanked by saints, is in Italy. The predella panels show, chronologically, the Resurrection of Lazarus, the Way to Calvary, the Descent from the Cross, and the Entombment. Originally, an image of the Crucifixion (now in Germany) would have been in the center. Throughout his career, Giovanni di Paolo referred to the pictorial tradition of his native Siena that was rooted in Byzantine art and is characterized by, in particular, the gold ground and the stylized rock formations. For more information on these panels, please see Federico Zeri's 1976 catalogue no. 78a-d, pp. 116-121.