The Laboratory of Natural Universe was executed by Sadequain during a three month period in 1961 to adorn the then new building of State Bank headquarter. This can easily be called a labor of love because of the painstaking technique used by the artist. It was done by scratching the paints with a knife to highlight its features which needed extreme care and patience. It depicts, as is apparent, human endeavor and man's quest for treasures of earth and heaven. The earth's Ecology, the organic bio-diversity of its ecosystem are all being investigated to add to human knowledge. The artist's brush and knife beautifully depict the thirst for knowledge of humankind.