Van Dyck probably painted this work in Antwerp c.1632, but it shows the influence of his stay in Italy (1621-25). The pious, moist-eyed gaze of the Virgin, particularly reminiscent of Guido Reni, reflects the artist's own intense Catholic religiosity.
Originally the composition was more compact, but the Dulwich canvas has been extended by a foot at the top, to make the work a pendant to DPG81, Charity.