The group of demonic figures attacking Saint Anthony was inspired by the Martin Schongauer engraving of the same subject from about 1475, though the extensive landscape is a fine example of Cranach's individual style. <em>The Temptation of Saint Anthony</em> has possible connections to the Chancellor of Wittenberg University, Goswin von Orsoy (1450-1515), who was also the preceptor of the Antonite monastery at nearby Lichtenburg. The group of buildings in the scene may represent this monastery, which was later destroyed; the monastery also owned a chapel in Wittenberg where there was an altarpiece of Saint Anthony.