Caroline Maria Applebee was an English artist, mostly in watercolour.
Born in London, but baptized at St Margaret's Church, Canterbury, on 16 May 1787, Caroline Maria Applebee was the eldest daughter of the Rev. John Applebee, a Church of England clergyman, by his marriage to Grace Lukyn. She never married and spent most of her life in and around Colchester. A graduate of St John's College, Oxford, her father was appointed a Prebendary of Lincoln in 1795 and the next year became Rector of East Thorpe, Essex, which brought the Applebee family to Colchester when Caroline Maria was about eleven. Her father died in 1825, aged 69.
Applebee was a friend of Charles Lamb, who addressed an acrostic to her which was first published in 1830. In 1834 she was a subscriber to the publication of Two Lectures on Taste, by Dr James Carter, in 1838 to the publication of a new translation of three plays by Lessing, and in 1841 to Emily Elizabeth Willement's A Bouquet from Flora's Garden. In 1841 and 1851 Applebee was recorded as living at 53, Crouch Street, Colchester, with several servants. In 1851 her rank or profession was stated as "Lady of merit".