Greenville is a city in Bond County, Illinois, United States, 51 miles east of St. Louis. The population as of the 2010 census was 7,000. It is the county seat of Bond County.
Greenville is part of the St. Louis Metropolitan Statistical Area. It is also considered part of the Metro East region of Illinois.
Greenville celebrated its Bicentennial in 2015 as one of the oldest communities in Illinois. It is home to Greenville University, the Richard Bock Museum, the American Farm Heritage Museum, the Armed Forces Museum and the Demoulin Museum and a federal prison, Federal Correctional Institution, Greenville. It is also home to internationally known companies, including Nevco Scoreboard, the largest privately owned scoreboard company in the world, and DeMoulin Brothers, the world's oldest and largest manufacturer of band uniforms.