Großlohra is a municipality in the district of Nordhausen, in Thuringia, Germany, situated on the northern edge of the Hainleite ridge about 20 km southwest of the district capital. It consists of the settlements of Friedrichslohra, Großwenden, Kleinwenden, as well as Münchenlohra with its former convent basilica St. Gangulphus and castle Lohra with its accompanying manor, all of which were united in 1950.