The House-Museum of Lope de Vega is a writer's house museum in the former home of the "golden age" writer Lope de Vega, located in Madrid, Spain.
The sixteenth-century house was bought by the writer in 1610. Today it is conserved by the Real Academia Española, which is the institution responsible for the regulation of the Spanish language. The Academy restored the house and opened it as a museum in 1935, the same year the building was declared a national monument. The building is currently protected as a Bien de Interés Cultural.
The Academía owns three of Lope de Vega's manuscripts on display at the museum.