Kotzebue or Qikiqtaġruk is a city in the Northwest Arctic Borough in the U.S. state of Alaska. It is the borough's seat, by far its largest community and the economic and transportation hub of the subregion of Alaska encompassing the borough. The population of the city was 3,201 as of the 2010 census, up from 3,082 in 2000. The city has received an All-America City award.