STS-95 was a Space Shuttle mission launched from Kennedy Space Center, Florida on 29 October 1998, using the orbiter Discovery. It was the 25th flight of Discovery and the 92nd mission flown since the start of the Space Shuttle program in April 1981. It was a highly publicized mission due to former Project Mercury astronaut and United States Senator John H. Glenn Jr.'s return to space for his second space flight. At age 77, Glenn became the oldest person to go into space, a record that remained unbroken for 23 years until 82-year-old Wally Funk flew on a suborbital flight on Blue Origin NS-16, launching on July 20, 2021. Glenn, however, remains the oldest person to reach Earth orbit. This mission is also noted for inaugurating ATSC HDTV broadcasting in the U.S., with live coast-to-coast coverage of the launch. In another first, Pedro Duque became the first Spaniard in space.
The mission's objectives involved investigating life-sciences experiments, using the SpaceHab module to perform these experiments on Senator Glenn.