Assmannshausen is, since the incorporation in 1977, a quarter of Rüdesheim am Rhein in the Rheingau, located on the Rhine in the state of Hesse, Germany. The village has a lithium spring, spa and a Kurhaus, and is famed for its red wine made from Pinot noir, which resembles red Burgundy wine. The Hessische Staatsweingüter Kloster Eberbach are running their VDP red wine estate in the village.
From Assmannshausen a chairlift ascends the Jagdschloss Niederwald where a 30 minutes hike leads to the Niederwalddenkmal.
The heritage-listed former winery Assmanshausen Winery in Queensland, Australia, was named after this region.