Francisco Javier de Balmis was a Spanish physician best known for leading an 1803 expedition to Spanish America and the Philippines to vaccinate populations against smallpox. His expedition is considered the first international vaccination campaign in history and one of the most important events in the history of medicine. It inspired recent vaccination efforts such as that of Carlos Canseco, president of Rotary International, to start the worldwide program PolioPlus to eradicate polio.