Cinquefrondi is a comune in the Metropolitan City of Reggio Calabria in the Italian region Calabria, located about 70 kilometres southwest of Catanzaro and about 50 kilometres northeast of Reggio Calabria.
Cinquefrondi borders the following municipalities: Anoia, Giffone, Mammola, Polistena, San Giorgio Morgeto. It is part of the Aspromonte National Park.