Noto Cathedral is a Roman Catholic cathedral in Noto in Sicily, Italy. Its construction, in the style of the Sicilian Baroque, began in the early 18th century and was completed in 1776. It is dedicated to Saint Nicholas of Myra, and has been the cathedral of the Diocese of Noto since the diocese's establishment in 1844.
The cathedral dome collapsed in 1996 as a result of unremedied structural weakening caused by an earthquake in 1990, to which injudicious building alterations in the 1950s may have contributed. It has since been rebuilt, and was reopened in 2007.