Maysville is a home rule-class city in Mason County, Kentucky, United States and is the seat of Mason County. The population was 9,011 at the 2010 census, making it the 40th-largest city in Kentucky by population. Maysville is on the Ohio River, 66 miles northeast of Lexington. It is the principal city of the Maysville Micropolitan Statistical Area, which includes Mason and Lewis counties. Two bridges cross the Ohio from Maysville to Aberdeen, Ohio: the Simon Kenton Memorial Bridge built in 1931 and the William H. Harsha Bridge built in 2001.
On the edge of the outer Bluegrass Region, Maysville is historically important in Kentucky's settlement. Frontiersmen Simon Kenton and Daniel Boone are among the city's founders. Later, Maysville became an important port on the Ohio River for the northeastern part of the state. It exported bourbon whiskey, hemp and tobacco, the latter two produced mainly by African American slaves before the Civil War. It was once a center of wrought iron manufacture, sending ironwork downriver to decorate the buildings of Cincinnati, Ohio, and New Orleans, Louisiana.